Vineet Awasthi
Assistant Professor Amity Institute of Biotechnology Amity University, Lucknow Campus Uttar Pradesh
Biography:
Abstract:
The diversity and complexity of the nanoparticles involved make nanotoxicology a very challenging field. Several parameters could influence the final biological response to nanomaterials in the environmental sector and nanomedicine. Nanoparticles interact with protein and help in the signal transduction, which stimulate the inflammatory response through the respiratory burst. This leads to the inbalance of redox homeostasis of the cells and cause oxidative stress which indicates that some other mechanism is involved when nanoparticles interact with the protein through the surface receptors and enter the physiological environment. The nanoparticles(NPs) rapidly get absorbed and bind to the protein and alter the biological system .It is interesting that acidity could favor dissolution and uptake of nanomaterials.