Rajaa SEGHIRI
Ibn Tofaïl University,Morocco
Title: In Vivo Wound Healing Activity of Spirulina platensis
Biography:
Dr has her expertise in evaluation and passion in Industrial Engineering, Food Science and Green Chemistry. She is interested mainly in valorization of algae in various industrial and research sectors for interest in food security. Her open and contextual evaluation studies based on nutritional, chemical, techno functional and biological verifying that creates new path ways for improving well being. She has a significant experience in research, evaluation and teaching both in university and education institutions.
Abstract:
Spirulina is a microalga used in traditional folk medicine in Morocco for the treatment of various health disorders. The wound healing activity of Moroccan Spirulina is unknown. In the current study, aqueous extracts of Spirulina platensis were investigated for acute toxicity and
wound healing activity in Swiss Albino mice and White New Zealand rabbits, respectively. The LD50 (amount of substance required to kill 50% of the test population) of the microalga was greater than 5,000 mg/kg. Healing after application of the same amount of ointment on differently induced (mechanical, chemical, and thermal) wounds was about the same, over five weeks. Aqueous extract had remarkable healing activity on rabbits’ skin, possessing significantly greater healing effect for mechanical and chemical burns than controls. Moreover, the hair growing time was faster in treated groups; Spirulina-treated groups did not show any contamination with microbes compared to others. This study affirms that Spirulina platensis can be considered as a potential therapeutic agent for wound healing not only as a complementary medicine but also in conventional medicine.